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The adrenal and thyroid glands perform vital functions to regulate important metabolic activities and to help us stay healthy. Observing a healthy diet can help ensure the proper functioning of these citizens of the endocrine system, but nutritional supplements may also help support their proper functioning. In this article, we review some useful individual supplement ingredients and some high-quality branded supplement formulations. Read on to find out more about the best adrenal and thyroid support supplements.

You may not often think of them, but your adrenal and thyroid glands play critical roles in the maintenance of your overall health.  Your thyroid gland is a butterfly-shaped organ located at the front of your neck.  Its many functions relate to metabolism, growth, body temperature, hormonal control, and mood.  Your adrenal glands rest on top of your kidneys, and control your immune function, blood pressure, blood sugar, reproductive hormones, and stress response.  The thyroid and adrenals are part of the endocrine system, a collection of glands and organs that produce hormones and send them into the bloodstream to regulate body functions.   

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Read on to discover why these glands are so important, what happens when their function is disrupted, and some of the best adrenal and thyroid support supplements.

Best Adrenal And Thyroid Support Supplements is an original (HerHealthWatch) article.

What happens when adrenal and thyroid functions are disrupted?

Any disruption to these important glands can cause a range of unpleasant symptoms.  The most common thyroid disorders are hyperthyroidism (overactive thyroid) and hypothyroidism (underactive thyroid).  If your thyroid is overactive, you may experience fast heart rate, weight loss, trouble sleeping, and diarrhea.  In contrast, an underactive thyroid can lead to fatigue, weight gain, constipation, slow heart rate, and fertility issues. 

Similarly, disorders of the adrenal gland cause a wide range of symptoms across multiple body systems.  These may include excessive fatigue, sweating, low blood pressure, low blood sugar, muscle and joint pain, irregular periods, and weight gain or weight loss.  Most notably, your adrenals release cortisol, which is sometimes called a ‘stress hormone.’  Cortisol is produced during the ‘fight-or-flight’ stress response, and it performs functions that would have helped our ancient ancestors manage dangerous situations.  For instance, cortisol stimulates the release of glucose from the liver for quick energy; it also suppresses nonessential functions like digestion, reproductive processes, and growth.  Imbalances in cortisol levels can lead to serious health issues like diabetes, cardiovascular disease, osteoporosis, or even psychiatric disorders.

Proper nutrition can help support the proper functioning of the thyroid and adrenals; however, often, we don’t consume enough vital nutrients from our diets, so supplements may be necessary.  We’ll take a look at the best adrenal and thyroid support supplements and some of their ingredients. 

Lady facing the adrenal gland problem.

Best adrenal and thyroid support supplements:

High potency B vitamins

The B vitamins are critical to the proper functioning of the endocrine system, and deficiency can lead to conditions like hyperthyroidism, adrenal cortex stress, and even high blood pressure.  Vitamin B5 (also known as pantothenic acid) is sometimes called the ‘stress reliever vitamin.’  B5 is critical for the proper functioning of the adrenal glands, and supplementing with this water-soluble vitamin can give your adrenals the support they need so they do not become overtaxed.  Most notably, vitamin B5 helps regulate cortisol levels in the blood, controlling them when they are too high and boosting them when they are too low.   

Fruits and vegetables contain vitamin B5

Best adrenal and thyroid support supplements:

Vitamin C

It is not well-known that most vitamin C in our bodies is stored in our adrenal glands, and adrenal function is compromised if we do not consume enough of this water-soluble nutrient.  Your adrenal glands require vitamin C to produce cortisol, and so you need to replenish your vitamin C if you’re under stress.  Vitamin C supplementation has even been shown to lower cortisol levels after periods of high stress.  So, this important nutrient can help your body to normalize if you’re experiencing chronic stress.

Citrus fruits are rich in vitamin C.

Best adrenal and thyroid support supplements:


While it’s best known for its role in immune support, zinc is also essential for the proper production of thyroid hormones.  Additionally, zinc supports the adrenals as it helps regulate the stress response.  A short-term decrease in cortisol levels has been seen in people taking zinc supplements, and some integrative medicine practitioners recommend taking this essential mineral in the evening to help with relaxation and ease of falling asleep. 

Multiple sources to obtain zinc.

Best adrenal and thyroid support supplements:

Rhodiola Rosea

Rhodiola Rosea is classified as an adaptogen, meaning that it helps to balance the body’s response to stress.  This means that Rhodiola can help balance your adrenal function, helping you feel energized when you would normally be exhausted, and calm when you would normally be anxious.  This herb is sometimes taken in the early stages of adrenal fatigue, and is known for its capacity to regulate cortisol levels.  Users may notice decreases in irritability and insomnia. 

Rhodiola Rosea helps to reduce the body's stress.

Best adrenal and thyroid support supplements:


Tyrosine is an amino acid used to make many hormones, including those produced by the thyroid and adrenal glands.  L-tyrosine is simply a synthetic version of this amino acid that can be taken as a supplement.  When you’re in a state of stress, your adrenals send dopamine, norepinephrine, and epinephrine into your bloodstream to help your body respond to the stressor.  Supplemental L-tyrosine can help prevent the depletion of these vital messengers, which in turn reduces the stress on your glands. 

A young girl is relaxing with a cup of tea.

Best adrenal and thyroid support supplements:

Five top brands

We’ve identified five top adrenal and thyroid support supplement brands:

Nutra Champs’ Balance: This thyroid and adrenal support formula contains 6250% DV of B12, plus zinc, L-tyrosine, Rhodiola Rosea, ashwagandha, and black pepper for potency. 

WELLPATH’s Soothe: Promising to support energy, metabolism, and stress response, this adrenal and thyroid support supplement contains vitamin B12, iodine, zinc, Rhodiola Rosea, ashwagandha, Eleuthero root, and black pepper for potency.

DR CHILDS’ Thyroid Adrenal Reset Complex:   This potent formula is a mix of adrenal glandulars, adaptogens, antioxidants, and pre-activated B vitamins. 

Gaia Herbs’ Adrenal Health Daily: This pared-down supplement contains a mix of adaptogenic herbs to maintain energy and balance stress.  Its ingredients include Rhodiola Rosea, Holy Basil, and ashwagandha. 

The Whole Journey’s Whole Daily+: This specially tailored multivitamin is designed to promote healthy energy, metabolism, and hormonal balance as it reduces inflammation.  It contains 20,833% DV of vitamin B12 plus 667% DV of vitamin C for optimal adrenal and thyroid support.  Other ingredients include pantothenic acid, iodine, and antioxidants. 

best adrenal and thyroid support supplements

Learn to trust your own body with The Whole Journey

Our search for the best adrenal and thyroid support supplements brought us to The Whole Journey, a standout wellness company founded and run by holistic nutritionist, Christa Orecchio.  The Whole Journey offers a wide range of comprehensive wellness programs (including a Hormone Balancing Program) designed to help its customers ‘heal from the root cause.’ 

With a focus on lasting change and true, deep healing, The Whole Journey offers courses designed to encourage people to use food as medicine and modify their lifestyles for optimal results.  Way more than just a supplement brand, this company offers a way of life.  As Orecchio stated in a recent interview: “The reason you can trust us is because we teach you how to trust yourself and your own body.”

Lasting results require lasting change

When you’re under stress, a cascade of stress hormones disrupts multiple body functions like digestion, immune response, and thyroid hormone production.  This is how being in a perpetual state of ‘fight-or-flight’ can have hormonal and metabolic consequences over time, as your susceptibility to disease increases.  Basic lifestyle changes like limiting caffeine, avoiding sugar, getting enough rest, and engaging in moderate exercise can all help to reduce your stress response and support your adrenals and thyroid. 

A balanced diet rich in lean proteins, vegetables, and whole grains can also help.  If you are doing everything right and you still feel the need for extra support, the market offers a range of supplements to help balance your adrenals and thyroid.  When you incorporate lasting change throughout your wellness journey, you’re sure to see the results you’ve been hoping for.

A girl with a smiling face.

Further Reading:

The Guardian:  My underactive thyroid was slowly killing me  

Harvard Stem Cell Institute: The mystery of the regenerating adrenal gland

Dr. Axe: Symptoms of Thyroid Problems & Remedies That Help

Important Note: The information contained in this article (Best Adrenal And Thyroid Support Supplements) is for general informational purposes only, and should not be construed as health or medical advice, nor is it intended to diagnose, prevent, treat, or cure any disease or health condition. Before embarking on any diet, fitness regimen, or program of nutritional supplementation, it is advisable to consult your healthcare professional in order to determine its safety and probable efficacy in terms of your individual state of health.

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